以细胞工程及其治疗学研究为特点的省级重点实验室，在科研、人才培养和社会服务中，形成了3个具有特色和优势的研究方向，拥有科研能力强的管理和专业技术团队，建立了较为完善的先进科研平台和平台开放管理机制。在长期坚持产学研用开放共享的过程中，实验室不断强化先进平台建设和技术水平提升；在贯彻国家有关细胞制剂研发政策与法规的同时，加强体系建设与规程的落实；通过基础学科与临床学科的融合发展，积极推进产学研用结合，通过科研基本技能培训和学术、技术交流，提升科研效益和科技产出质量，坚持“三级管理”，推进科研“学术带头人负责制”与平台技术“技术负责人负责制”，以临床需求为纽带，促进学科群发展与合作共赢，通过新兴交叉学科建设与研究方向交叉，促进前沿科学研究、临床技术孵化、产业资源存储、干细胞新药研发与高层次人才培养的协调发展。因此，面向创新型国家建设和高质量发展的新形势和新要求，本文旨在分享省级重点实验室细胞工程技术平台开放共享20年的主要管理和运行经验，并结合“产学研用”案例，提供学科交叉、协同创新的服务医疗需求的实践探索与思考。

The provincial key laboratory, which is characterized by cell engineering and therapeutics research, has formed three research directions with characteristics and advantages in scientific research, personnel training and social service. The laboratory has a management and professional technical team with strong scientific research ability, and has established a relatively perfect advanced scientific research platform and platform open management mechanism. In the long-term process of adhering to opening and sharing, the laboratory has continuously strengthened the management and technical team construction. Strengthen the system construction and the implementation of regulations while implementing the national policies and regulations on cell preparation research and development. Through the fusion and development of basic and clinical subjects, we actively promote the combination of the efforts of industry, academia, research and application. Through the basic skills training and academic exchange, we improve the scientific research efficiency and scientific and technological output quality. On the basis of adhering to the "three-level management", "the academic leaders responsibility system" of scientific research and "the technical head responsibility system" of platform technology were promoted. And clinical needs as a link to promote the development of disciplines and win-win cooperation. To promote the coordinated development of frontier scientific research, clinical technology research incubation industrial resource storage, stem cell drug research and development, and high-level personnel training through the construction of new interdisciplinary disciplines and overlapping research directions. Therefore, in the face of the new situation and new requirements for the construction of an innovative country and high-quality development, this paper aims to share the main management and operation experience of the provincial key laboratory cell engineering technology platform for 20 years, and combined with the cases of "industry, academia, research and application", to provide practical exploration and reflection on interdisciplinary and collaborative innovation to serve medical needs.