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Chinese Journal of Clinical Laboratory Management(Electronic Edition) ›› 2015, Vol. 03 ›› Issue (03): 139-145. doi: 10.3877/cma.j.issn.2095-5820.2015.03.003

Special Issue:

• Review • Previous Articles     Next Articles

Application of next generation sequencing in cancer precision medicine

Xudong Wang, Shaoqing Ju   

  • Received:2015-08-19 Online:2015-08-28 Published:2015-08-28
  • Contact: Shaoqing Ju
  • About author:
    Corresponding author: Ju Shaoqing, Email:

Abstract:

In precision medicine. whole genome sequencing data, related molecular information and individual clinical data, are often employed forselecting appropriate and optmal therepiesbased on the contect of a patient′s genetic conten, and then prepare for the development of targeted drugs and achieve accurate medical care. At present, the concept of precision medicine is infiltrating into the fields of clinical tumor diagnosis and treatment. Tumor will be diagnosed and classified according to underlying molecular and related factors to achieve "treating the same disease with different governance" and "treating different diseases with the same protocol". In addition, the next generation sequencing(NGS) technology will be an indispensable technology in precision medicine, which promotes the application of precision medical treatment in the clinical setting. Mereover, it also need to improve the regulatory policies, to achieve the goal of standardized management of NGS in clinical application.

Key words: Next generation sequencing, Cancer, Precision medicine

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