To study the characteristics of the teaching process of medical laboratory specialty and to compile and publish excellent characteristic teaching materials are important measures to deepen the reform of teaching materials, promote the teaching reform with the innovation of teaching material and improve the quality of medical education. Based on the compilation process of the clinical practice teaching textbook Knowledge and Skills of Clinical Biochemistry Laboratory (first edition) published by People's Medical Publishing House, we analyzed the limitations of the textbooks used in clinical practice teaching, and put forward the basic idea of clinical practice teaching, explores the new teaching material in the writing concept, system, content, form and function characteristic and innovation.