The clinical significance of eosinophil count in patients with allergic rhinitis

doi:10.3877/cma.j.issn.2095-5820.2021.03.003

Abstract

Abstract:

Objective

To investigate the clinical value of peripheral blood eosinophil count in the auxiliary diagnosis of children with allergic rhinitis.

Methods

117 children with allergic rhinitis diagnosed in the First Affiliated Hospital of Guangzhou Medical University and 118 healthy children from the physical examination of the Maternal and Children Health Care Hospital in Yuexiu District in Guangzhou were collected through retrospective analysis, and the correlation analysis was conducted based on the resultes ofthe severity of allergic rhinitis and Visual Analog Scale.

Results

Compared with healthy children, peripheral blood eosinophil count were higher in children with allergic rhinitis. The number of eosinophil in patients with allergic rhinitis was correlated with tIgE、eye itching and sneezing. There was a statistically difference in the correlation between eosinophil count and symptom in different degrees of allergic rhinitis.

Conclusions

Peripheral blood eosinophil count can assist in the diagnosis of allergic rhinitis, and combined with tIgE can reflect the severity of allergic rhinitis.

Key words: Allergic rhinitis, Eosinophilia, Children, Visual Analog Scale

Xinrui Zeng, Jiamin Liang, Yijie Wang, Yun Chen, Jiaying Luo, Feng Wang, Baoqing Sun. The clinical significance of eosinophil count in patients with allergic rhinitis[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2021, 09(03): 138-142.

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https://zhlcsysgldzzz.cma-cmc.com.cn/EN/Y2021/V09/I03/138

Figures/Tables 6

指标	AR组	对照组
淋巴细胞( $109$ /L)	3.07(2.60，3.99)	3.38(2.89，4.20)
EOS( $109$ /L)	0.35(0.18，0.57)^a	0.24(0.15，0.49)
嗜碱性粒细胞( $109$ /L)	0.03(0.02，0.05)	0.03(0.02，0.04)
中性粒细胞( $109$ /L)	2.99(2.51，4.08)	2.98(2.58，3.94)
ELR	0.11(0.05，0.18)^a	0.07(0.05，0.15)
BLR	0.01(0.01，0.01)	0.01(0.01，0.01)
NLR	0.95(0.72，1.24)	0.88(0.68，1.21)

指标	AR组	对照组
淋巴细胞( $109$ /L)	3.07(2.60，3.99)	3.38(2.89，4.20)
EOS( $109$ /L)	0.35(0.18，0.57)^a	0.24(0.15，0.49)
嗜碱性粒细胞( $109$ /L)	0.03(0.02，0.05)	0.03(0.02，0.04)
中性粒细胞( $109$ /L)	2.99(2.51，4.08)	2.98(2.58，3.94)
ELR	0.11(0.05，0.18)^a	0.07(0.05，0.15)
BLR	0.01(0.01，0.01)	0.01(0.01，0.01)
NLR	0.95(0.72，1.24)	0.88(0.68，1.21)

症状指标	评分(分)
打喷嚏	3.00(2.00，4.50)
流鼻涕	3.00(2.00，5.00)
鼻塞	4.00(1.00，6.00)
鼻痒	4.00(2.00，5.00)
眼痒	2.00(0.00，4.00)
结膜充血	0.00(0.00，2.00)
流泪	1.00(0.00，1.00)
嗅觉失调	0.00(0.00，1.00)
眼脸水肿	0.00(0.00，1.00)
对睡眠的影响	2.00(1.00，5.00)
对工作或学习的影响	2.00(1.00，4.50)
对社会活动的影响	2.00(0.00，3.00)
对体力活动的影响	2.00(0.00，3.00)
对生活影响总分	8.00(4.00，14.00)
症状总分	20.97±12.10

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