Abstract:
Objective To analyze the comparative results of prothrombin time (PT) and activated partial thromboplastin time (APTT) in different SYSMEX coagulation analyzers.
Methods PT and APTT were detected in three instruments (two of Sysmex CA7000 and one was CA1500). The comparative analysis of test results by industry standards WS/T407-2012 and WS/T406-2012.
Results Using the scheme WS/T407-2012, the relative deviations of PT and APTT of sample one were 7.10% and 5.20%, respectively; the relative deviations of sample two were 5.74% and 2.46%, respectively; both were less than the comparative request of 7.50%. Using the scheme WS/T406-2012, 20 samples were detected by the three instruments, the relative deviation <7.50% and the coincidence rate≥80% set as the standard. Compared with the benchmark instrument CA7000, the coincidence rates of PT and APTT in CA1500 were 85% (17/20) and 80% (16/20), respectively; those in CA7000-2 were 85% (17/20) and 90% (18/20), respectively.
Conclusions According to these two kinds of schemes comparative methods, the determination results of PT and APTT in three detection systems are comparable. The laboratory might choose appropriate solutions for instruments alignment according to the actual situation in order to ensure the result comparability.
Key words:
Health industry standards,
Comparison instruments,
Prothrombin time,
Activated partial thromboplastin time
Yanqun Wang, Yuan Cao, Chengjin Hu. Comparative analysis of prothrombin time and activated partial thromboplastin time results in different blood coagulation analyzers by industry standards[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2015, 03(04): 240-243.