Tracking the hospital-acquired infections outbreak of multi-drug resistant bacteria with whole genome sequencing

doi:10.3877/cma.j.issn.2095-5820.2016.03.002

Abstract

Abstract:

The development of next-generation high-throughput sequencing technology promotes the growth of microbial genomics increasingly. Whole-genome sequencing (WGS) has been considered as a promising tool for tracking and tracing transmission pathways in outbreaks caused by multidrug-resistant bacteria. This hot spot of clinical microbial research has developed a burgeoning academic field dubbed genomic epidemiology. Based on the powerful discriminatory capability in molecular typing and abundant data from WGS, people could identify the homology of multidrug-resistant bacteria at great length, elucidate their novel transmission route and decipher their evolution process in the hospital environment. They are significant for clinical infections control.

Key words: Whole-genome sequencing, Multidrug-resistant bacteria, Outbreak, Tracking, Tracing

Yan Jiang, Yunsong Yu. Tracking the hospital-acquired infections outbreak of multi-drug resistant bacteria with whole genome sequencing[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2016, 04(03): 134-138.

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References 12

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