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中华临床实验室管理电子杂志 ›› 2015, Vol. 03 ›› Issue (03) : 160 -167. doi: 10.3877.cma.j.issn.2095-5820.2015.03.006

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综述

多发性骨髓瘤的靶向治疗新进展
陈霄磊, 陈文明   
  • 收稿日期:2015-07-20 出版日期:2015-08-28
  • 通信作者: 陈文明

Progress of targeted therapy for multiple myeloma

Xiaolei Chen, Wenming Chen   

  • Received:2015-07-20 Published:2015-08-28
  • Corresponding author: Wenming Chen
  • About author:
    Corresponding author: Chen Wenming, Email:
引用本文:

陈霄磊, 陈文明. 多发性骨髓瘤的靶向治疗新进展[J]. 中华临床实验室管理电子杂志, 2015, 03(03): 160-167.

Xiaolei Chen, Wenming Chen. Progress of targeted therapy for multiple myeloma[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2015, 03(03): 160-167.

近年来,多发性骨髓瘤(multiple myeloma,MM)的治疗已由化疗时代进入靶向治疗时代,靶向治疗是针对骨髓微环境中骨髓瘤细胞生长进行特异性杀伤的治疗方法,随着对MM研究的深入,国内外开发了许多新药,新的化疗联合方案也不断涌现,临床应用免疫调节剂、蛋白酶体抑制剂为基础的单药或联合方案治疗MM已经取得良好疗效,为患者带来了新的希望。

In recent years, the treatment of multiple myeloma (MM) has progressed from the era of chemotherapy into the targeted therapy times, the targeted therapy focus on inhibiting the myeloma cell growth and survival in the bone marrow microenvironment. With the further investigation of MM, numerous novel agents and new regimens of combined chemotherapy are currently emerging. The clinical application of Immunomodulatory drugs (IMids), proteasome inhibitor based single or combined regimens has had profound effects a MM therapy, which promises for MM patients.

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