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中华临床实验室管理电子杂志 ›› 2018, Vol. 06 ›› Issue (01) : 10 -14. doi: 10.3877/cma.j.issn.2095-5820.2018.01.004

所属专题: 文献

专题笔谈

肠道微生态研究技术在代谢综合征中的应用
曹会玲1, 吴尚为2,()   
  1. 1. 300203 天津医科大学检验学院
    2. 300203 天津医科大学检验学院;300100 天津市南开医院
  • 收稿日期:2017-09-11 出版日期:2018-02-28
  • 通信作者: 吴尚为

Application of the technology of gut microbial ecology in the metabolic syndrome

Huiling Cao1, Shangwei Wu2,()   

  1. 1. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300203, China
    2. School of Laboratory Medicine, Tianjin Medical University, Tianjin 300203, China; Tianjin Nankai Hospital, Tianjin 300100, China
  • Received:2017-09-11 Published:2018-02-28
  • Corresponding author: Shangwei Wu
  • About author:
    Corresponding authors: Wu Shangwei, Email:
引用本文:

曹会玲, 吴尚为. 肠道微生态研究技术在代谢综合征中的应用[J/OL]. 中华临床实验室管理电子杂志, 2018, 06(01): 10-14.

Huiling Cao, Shangwei Wu. Application of the technology of gut microbial ecology in the metabolic syndrome[J/OL]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2018, 06(01): 10-14.

哺乳动物肠道内定居着数量庞大且组分复杂的微生物群,它们共同构成了肠道微生物组。近年来,人们逐渐认识到肠道微生物与一些疾病的发生和发展密切相关,如代谢性疾病、炎症性肠病、肿瘤、免疫系统以及神经系统疾病等,使得肠道微生物成为研究的热点。迅猛发展的微生物研究技术为我们提供了高效有力的技术平台,推动了对肠道微生态的系统认知,也为疾病的诊断及治疗开辟了新思路。本文旨在总结与分析目前常用微生态研究技术的最新进展及其局限性,为进一步的肠道微生物组研究提供参考,并简要介绍肠道微生态与代谢综合征的相关研究成果。

The intestinal tract of mammals has a large number of complex microbial flora, which together forms the intestinal microbiome. In recent years, it has been realized that intestinal microbes are closely related to the occurrence and development of some diseases, such as metabolic syndrome, inflammatory bowel disease, cancer, immune system and nervous system disease and so on, which makes intestinal microbiome to be one of the most active research fields. The rapid development of microbial research technologies provides us with efficient and powerful methodology and promotes the systematic understanding of intestinal micro-ecology, and opens up new ideas for the diagnosis and treatment of diseases.. This review aims to summarize and analyze the latest progress and limitation of micro-ecological research techniques, providing a reference for further study of gut microbiota, and simply introduce the representative results of the study on the correlation between micro-ecology and metabolic syndrome in intestinal tract.

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