Research advance of microRNA in HIV-1 infection and related diseases

doi:10.3877/cma.j.issn.2095-5820.2019.01.005

Abstract

Abstract:

MicroRNA (miRNA) is an important post-transcriptional gene expression regulator, and its expression profile changes are related to many human pathology. The correlation between miRNA and human immunodeficiency virus 1 (HIV-1) has become one of the hot spots in global research. In this paper, the effects of miRNA on the transcription replication and latent infection of HIV-1 virus, the study of miRNA in HIV-1 related diseases and the therapeutic prospects of AIDS are reviewed.

Key words: microRNA, HIV-1, Virus replication, Latent infection, Therapy

Xinli Yan, Yuming Wang, Xiaofei Li, Runwu Zhang, Hongying Wang. Research advance of microRNA in HIV-1 infection and related diseases[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2019, 07(01): 17-21.

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