To investigate the value of procalcitonin (PCT) in the treatment of patients with COVID-19.

399 patients with COVID-19 treated in the Eighth People's Hospital of Guangzhou from January to March 2020 were selected as the study subjects, There were 343 mild cases and 56 severe cases.The cumulative number of PCT tests is 798.29 healthy people were selected as the control group. To test the PCT level in each group and compare with each other.

The level of serum PCT in the severe group was higher than that in the control group or the mild group. The level of PCT in COVID-19 with bacterial infection was higher than that in COVID-19 with organ failure or COVID-19 alone.

When COVID-19 patients had organ failure or combined with bacterial infection, the serum PCT level could be increased in different degrees. Continuous monitoring of serum PCT levels is still useful in the treatment of patients with COVID-19.