To evaluate the diagnostic value of commonly used infectious indicators in neonatal urinary infectious diseases, which might provide an effective laboratory research basis for clinical diagnosis and treatment of neonatal urinary tract infection.

Retrospective analysis was conducted on the laboratory and clinical data of the children with urinary bacteria culture records hospitalized in our hospital in recent 5 years. Clinical data and laboratory data of urinary bacteria culture positive group and culture negative group were compared.

The positive rate of urine culture in our hospital was 5.15%(83/1611) in recent 5 years, and the proportion of male neonates was higher than female neonates in urine culture positive neonates (68.67% vs 31.33%). Fever (24.10%) and jaundice (32.53%) were the most common clinical manifestations, but ther is no statistically different between groups; Urinary WBC count of culture positive group was significantly higher than culture negative group, but there is no statistical difference between groups in terms of blood WBC、CRP、PCT.

The diagnostic value of blood WBC、CRP、PCT are limited in the diagnosis of neonatal urinary tract infection, and combined use of routine urine test and urine culture is still a better diagnostic criterion for neonatal urinary tract infection.