The roles of exosomes in chronic obstructive pulmonary disease

doi:10.3877/cma.j.issn.2095-5820.2023.01.009

Abstract

Abstract:

Chronic obstructive pulmonary disease (COPD) has a high morbidity and mortality worldwide and is characterized by chronic inflammation and progressive airflow obstruction. At present, no drug treatment has been proved to improve the survival rate of COPD patients. In recent years, exosomes have become a research hotspot due to their involvement in inflammatory response, immune regulation and injury repair. At the same time, studies have found that exosomes are closely related to the occurrence and development of COPD. This review first introduced the biological characteristics components and functions of exosomes, and then lists the relevant studies on exosomes in COPD biomarkers and pathogenesis, and finally clarifies the latest progress of exosomes in clinical diagnosis and treatment of respiratory diseases.

Key words: chronic obstructive pulmonary disease, exosomes, miRNA, pathogenesis, biomarkers

Min Wang, Yan Zhang, Yingxi Wang, Long Zhao, Shuyue Xia. The roles of exosomes in chronic obstructive pulmonary disease[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2023, 11(01): 45-51.

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References 52

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