Abstract:

Cardiovascular and cerebrovascular diseases become the primary cause of death worldwide，of which atherosclerosis is a basis pathological procedure. Sorts of biomarkers participate in the process of atherosclerosis plaque formation，the most common are lipoproteins like low-density lipoprotein（LDL），high-density lipoprotein（HDL），apolipoprotein A（ApoA），ApoB and lipoprotein a［Lp（a）］，inflammation factors like homocysteine （HCY），reactive protein （CRP），interleukin （IL-6），Lp-PLA2，intercellular adhesion molecular-l （ICAM-1），tumor necrosis factor（TNF），fibrinogen（FIb），neoprerin（NPT），monocyte chemoatt-ractant protein-1 （MCP-1），chtinase-3-like-l protein（YKL-40），macrophage inhibition factor（MIF），coagulation factors like von Willebrand factor（vWF），and D-dimer（D-D）.Combining detection of these biomarkers is helpful for deter mining the clinical progress of atherosclerosis.

Key words: Atherosclerosis, Biomarker, Risk assessment