Analysis of HPV typing results in 24 597 women screened for cervical cancer in Heilongjiang Province

doi:10.3877/cma.j.issn.2095-5820.2019.04.008

Abstract

Abstract:

Objective

To analyze human papillomavirus (HPV) infection in Heilongjiang Province so as to provide some reference for the prevention and treatment of cervical cancer.

Methods

A total of 23 types of HPV were detected by reverse dot hybridization (RPH) with polymerase chain reaction (PCR) from 24 597 female cervical exfoliated cell specimens collected during January 2018 to October 2018.

Results

The positive rate of HPV was 32.16%, among which the high-risk typeaccounted for 77.33%. There were significant differences among single type infection rate and multiple type infection rate (P<0.01). According to age, HPV was divided into six groups, and the positive rate was U-shaped curve. The top five types with higher infection rate were type 16, 52, 58, 53, 51, and the infection rate were 5.04%, 3.34%, 3.00%, 2.92% and 2.31% respectively.

Conclusions

HPV infection in women is mainly high-risk type, which is closely related to age. The infection rate of women under 30 years old and over 50 years old is significantly higher. This study provides some reference for the HPV detection and cervical cancer screening.

Key words: Human papillomavirus, Cervical cancer, Age stratification

Lina Ma, Haibo Fan, Juntao Zhang, Shengnan Li. Analysis of HPV typing results in 24 597 women screened for cervical cancer in Heilongjiang Province[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2019, 07(04): 223-225.

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URL: https://zhlcsysgldzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-5820.2019.04.008

https://zhlcsysgldzzz.cma-cmc.com.cn/EN/Y2019/V07/I04/223

Figures/Tables 4

References 8

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排序	型别	阳性总数(例)	阳性率(%)
1	16	1257	5.04
2	52	1083	4.34
3	58	747	2.99
4	53	728	2.92
5	81	690	2.76
6	51	576	2.31
7	56	549	2.20
8	42	510	2.04
9	43	494	1.98
10	6	479	1.91
11	59	477	1.91
12	68	437	1.75
13	66	415	1.66
14	18	358	1.43
15	33	358	1.43
16	11	320	1.28
17	31	298	1.19
18	35	284	1.14
19	39	274	1.10
20	45	148	0.59
21	73	126	0.50
22	82	84	0.34
23	83	81	0.32

排序	型别	阳性总数(例)	阳性率(%)
1	16	1257	5.04
2	52	1083	4.34
3	58	747	2.99
4	53	728	2.92
5	81	690	2.76
6	51	576	2.31
7	56	549	2.20
8	42	510	2.04
9	43	494	1.98
10	6	479	1.91
11	59	477	1.91
12	68	437	1.75
13	66	415	1.66
14	18	358	1.43
15	33	358	1.43
16	11	320	1.28
17	31	298	1.19
18	35	284	1.14
19	39	274	1.10
20	45	148	0.59
21	73	126	0.50
22	82	84	0.34
23	83	81	0.32

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