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Chinese Journal of Clinical Laboratory Management(Electronic Edition) ›› 2023, Vol. 11 ›› Issue (02): 105-108. doi: 10.3877/cma.j.issn.2095-5820.2023.02.008

• Investigation • Previous Articles     Next Articles

Analysis of the current situation of human papillomavirus infection in females in Shanxi Province

Yu Qin(), Miao Yang, Kai Chang, Shuning. Wang   

  1. Taiyuan Jinyu Clinical Laboratory Co., Ltd, Taiyuan Shanxi 030032, China
  • Received:2022-05-27 Online:2023-05-28 Published:2023-06-29
  • Contact: Yu Qin

Abstract:

Objective

Persistent infection of high-risk human papillomavirus is the main cause of cervical cancer, so HPV typing test has a defensive effect on the early screening of cervical cancer. This paper mainly analyzes the infection situation of different types of HPV in women in Shanxi Province.

Methods

A total of 48 661 samples of HPV screening at Taiyuan Jinyu Clinical Laboratory Co., Ltd were selected from October to December 2021 and statistically analyzed by reverse point hybridization.

Results

The rate of HPV-positive infection in 48 661 cervical detached cell samples was 20.57%, including 17.73% for high-risk HPV infection and 5.22% for low-risk HPV infection. The number of HPV infected persons with single type was more than that of multi-type co-infected patients, among which the single high-risk type was the majority (58.67%), followed by the mixed high-risk types (15.94%). Among the 23 HPV genotypes, high-risk HPV types are susceptible to infection: HPV52, 16, 53, 58, 51 and 56; low-risk HPV types are susceptible to infection: 81, 42, and 43. Analysis of the infection in 5 age groups showed that the infection rate of women over 55 years old was the highest (32.63%).

Conclusions

From the above data, it can be found that the HPV infection rate of women over the age of 55 in Shanxi Province is relatively high. It is necessary to strengthen the publicity of cervical cancer and the relationship between HPV, regular HPV screening, and early detection and treatment of cervical precancerous lesions, so as to effectively prevent the occurrence of cervical cancer.

Key words: human papillomavirus, high-risk HPV, low-risk HPV, multi-type co-infection

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