Based on the experience and thinking of the clinical examination skill competition in Chengdu Medical College, we made a synthesis about the school-company co-education modes, practical teaching reform about professional core ability, the skill game promoting professional training. In the new era, the skill competition held by school together with company was a good supporter improving undergraduate co-education modes of medical examination technology for local applied undergraduate college. To achieve the goal of talent training accompanied with industry demand and local economic development, the collaborative education concept on integration of industry and education was used in the whole process of talent training. These measures could promote the integration of professional chain with industrial chain and innovation chain. The "examination +" compound talents with solid professional theory, excellent practical skills and strong innovative thinking should be brought up.