To explore the application effect of PDCA circulation in nursing management of venous blood specimens.

The information software was used to compare the changes of unqualified venous blood samples from inpatients in our hospital from January to August 2020 (before improvement) and from January to August 2021 (after improvement), and PDCA cycle management was used to manage unqualified venous blood samples, so as to continuously improve specimen quality.

From January to September in 2020, 750 349 inpatients were examined, and the unqualified rate was 21.03/10 000 (1578/750 349). After the application of information software combined with PDCA cycle management from January to September in 2021, the unqualified rate was reduced to 17.78/10 000 (1903/1 070 498). Comparison before and after improvement, there were statistically significant differences in total sample rejection rate, anticoagulant sample agglutination rate, blood culture contamination rate, patient identification error rate, sample damage rate during transportation, and sample collection timing error rate (χ² = 24.4732, 322.9718, 22.0901, 14.9955, 8.4113, 302.7255; P＜0.05). And the unqualified rate of venous blood samples in ICU, neonatology department, pediatric department and infection department showed a trend of gradual decline after rectification.

The application of information software combined with PDCA cycle management can effectively reduce the unqualified rate of venous blood samples of inpatients in our hospital, improve the quality of nursing management and ensure the quality before inspection, greatly reduce the waste of medical resources, and improve the operation efficiency of the hospital, so it is worth popularizing and applying.