To evaluate the incubation time and antibacterial adsorption properties of culture bottles of Meriere activated carbon and resin with different adsorption media.

The incubation time of bacterial strains simulated bacteremia samples in vitro was used to detect the positive detection time. On the basis of the simulated bacteremia samples, antibiotics such as genamicin, levofloxacin, vancomycin and meropenem were added. The antibacterial adsorption capacity of two different adsorption media culture jars was evaluated by the incubation time.

Time to detection of culture bottle: (1) In the aerobic bottle group, the positive detection time of resin bottle was shorter than that of activated carbon bottle, especially the growth rate of Enterococcus faecium and Escherichia coli was faster in resin bottle, and the difference between them was statistically significant (P=0.040). (2) In the anaerobic bottle group, the positive detection time of resin bottle was not significantly better than that of activated carbon bottle, and there was no statistical difference between them (P=0.638). (3) In the children's bottle group, the positive detection time of resin bottle was more obvious. The positive detection time of Staphylococcus aureus cultured in two bottles was significantly different, and there was a statistical difference between them (P=0.040). The adsorption performance of antibiotics: (1) The positive detection time of resin aerobic bottle in Gentamicin group, levofloxacin group and vancomycin group was shorter than that of activated carbon aerobic bottle, and there was statistical difference between them (P＜0.001). (2) In gentamicin group, the positive detection time of resin anaerobic bottle was not significantly different from that of activated carbon anaerobic bottle, and there was no statistical difference between them (P=0.822). The positive detection time of resin anaerobic bottle in levofloxacin group was longer than that of activated carbon anaerobic bottle, and there was statistical difference between them (P＜0.001). (3) In vancomycin group and meropenem group, resin anaerobic bottles reported positive within the specified time, while activated carbon anaerobic bottles reported negative, and there was a statistical difference between the two groups (P＜0.001). (4) The positive detection time of resin bottles in gentamicin group, levofloxacin group and vancomycin group was shorter than that in activated carbon bottles, and there was statistical difference between the two groups (P＜0.001).

The positive detection time of Meriere resin aerobic bottle and resin children's bottle is shorter than that of activated carbon aerobic bottle and activated carbon children's bottle, indicating that their adsorption capacity of antibacterial drugs is stronger. The advantage of resin anaerobic bottle in the positive detection time is not obvious compared with activated carbon anaerobic bottle, and resin anaerobic bottle has better adsorption effect on meropenem and vancomycin. The adsorption of gentamicin was not significant compared with that of activated carbon anaerobic bottle, and the adsorption of levofloxacin on resin anaerobic bottle was not as good as that of activated carbon anaerobic bottle.