新型冠状病毒核酸检测为新型冠状病毒感染的防控起到了重要作用。在新型冠状病毒核酸检测过程中，实验室防污染是个备受重视的质量问题，是保证新型冠状病毒核酸检测质量的重要因素。核酸扩增实验室的污染源有多种，其中因阳性质控品造成的污染是实验过程中最难处理的一种污染问题。本文针对新型冠状病毒核酸检测过程中可能存在的质控品污染从污染途径、发生原因、去污染措施、效果监测等方面进行详细的分析和讨论，从质控品污染角度为相关实验室提供一些实验室防污染的措施及应对办法。

Nucleic acid detection of SARS-CoV-2 plays an important role in the prevention and control of COVID-19. During the process of the nucleic acid detection of SARS-CoV-2, prevention of laboratory contamination is an important quality issue, which is a key factor to guarantee the quality of nucleic acid detection of SARS-CoV-2. There are many kinds of contamination sources in PCR laboratory, among which contamination caused by positive control is the most difficult to deal with in the experimental process. In this paper, the possible contamination of positive control during the process of nucleic acid detection of SARS-CoV-2 was analyzed and discussed in detail from the aspects of contaminating ways, causes, decontamination measures and effect monitoring, so as to provide some effective decontamination measures and countermeasures for PCR laboratory from the perspective of contamination from positive control.