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中华临床实验室管理电子杂志 ›› 2016, Vol. 04 ›› Issue (03) : 164 -167. doi: 10.3877/cma.j.issn.2095-5820.2016.03.008

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综述

流感病毒感染的实验室诊断进展
崔京涛1, 倪安平1,()   
  1. 1. 100730 中国医学科学院 北京协和医学院检验科
  • 收稿日期:2016-08-11 出版日期:2016-08-28
  • 通信作者: 倪安平

Laboratory diagnosis of influenza virus infection

Jintao Cui1, Anping Ni1,()   

  1. 1. Department of Clinical Laboratories, Peking Union Medical College Hospital, the Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
  • Received:2016-08-11 Published:2016-08-28
  • Corresponding author: Anping Ni
  • About author:
    Corresponding author: Ni Anping, Email:
引用本文:

崔京涛, 倪安平. 流感病毒感染的实验室诊断进展[J/OL]. 中华临床实验室管理电子杂志, 2016, 04(03): 164-167.

Jintao Cui, Anping Ni. Laboratory diagnosis of influenza virus infection[J/OL]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2016, 04(03): 164-167.

尽管流感疫苗应用已有很大进展,但流感仍对公共健康是一大威胁。历史上的流感多次大流行,以及每年季节性流感造成的严重感染和死亡备受关注。流感早期准确的实验室诊断对于尽早使用神经氨酸酶抑制剂药物治疗,以及控制感染至关重要。本文介绍的流感病毒实验室诊断技术包括病毒培养、抗原检测、核酸检测和血清学检测及进展。

Despite the significant advancement in vaccine, influenza continues to be a threaten to public health. Influenza has caused serious morbidities and mortalities both during yearly seasonal epidemics and historic pandemics. Early and accurate laboratory diagnosis to influenza virus is critical for initiation of antiviral therapy with neuraminidase inhibitors and for control of the infection. We discuss currently available approaches of laboratory diagnosis for influenza, in which viral culture, antigen detections, nucleic acid amplification tests and serology are included.

1
Jorgensen JH, Pfaller MA. Manual of clinical microbiology.11th ed [M]. Washington DC: American Society for Microbiology, 2015:1470-1486.
2
Jiang WM, Wang SC, Peng C, et al. Identification of a potential novel type of influenza virus in Bovine in China [J]. Virus Genes, 2014, 49(3):493-496.
3
Ferguson L, Eckard L, Epperson WB, et al. Influenza D virus infection in Mississippi beef cattle [J]. Virology, 2015,486:28-34.
4
Horimoto T, Hiono T, Mekata H, et al. Nationwide Distribution of Bovine Influenza D Virus Infection in Japan [J]. PLoS One, 2016, 11(9):e0163828.
5
Liu D, Shi W, Shi Y, et al. Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses [J]. Lancet, 2013,381(9881):1926-1932.
6
倪安平,王孟昭,李勇. 离心培养直接荧光染色法在流感病毒检测中的应用[J]. 中华检验医学杂志, 2003,26:346-348.
7
赵红,吕燕,杨国栋, 等. 2010-2013年济南市流行性感冒监测分析[J]. 中国预防医学杂志, 2015,16(11): 6896-6898.
8
Ginocchio CC, Zhang F, Manji R, et al. Evaluation of multiple test methods for the detection of the novel 2009 influenza A (H1N1) during the New York City outbreak [J]. J Clin Virol, 2009,45(3):191-195.
9
Matthey S, Nicholson D, Ruhs S, et al. Rapid detection of respiratory viruses by shell vial culture and direct staining by using pooled and individual monoclonal antibodies [J]. J Clin Microbiol, 1992, 30(3):540-544.
10
秦铭,田曼,夏雯, 等. 儿童社区获得性肺炎的病原学研究[J]. 临床儿科杂志, 2009,26(4):312-315.
11
Abraham MK, Perkins J, Vilke GM, et al. Influenza in the Emergency Department: Vaccination, Diagnosis, and Treatment: Clinical Practice Paper Approved by American Academy of Emergency Medicine Clinical Guidelines Committee [J]. J Emerg Med, 2016,50(3):536-542.
12
Eggers M, Enders M, Terletskaia-Ladwig E. Evaluation of the Becton Dickinson Rapid Influenza Diagnostic Tests in Outpatients in Germany during Seven Influenza Seasons [J]. PLoS One, 2015,10(5):e0127070.
13
Moesker FM, van Kampen JJ, Aron G, et al. Diagnostic performance of influenza viruses and RSV rapid antigen detection tests in children in tertiary care [J]. J Clin Virol, 2016,79:12-17.
14
Busson L, Hallin M, Thomas I, et al. Evaluation of 3 rapid influenza diagnostic tests during the 2012-2013 epidemic: influences of subtype and viral load [J]. Diagn Microbiol Infect Dis, 2014,80(4):287-291.
15
Harper SA, Bradley JS, Englund JA, et al. Seasonal influenza in adults and children--diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America [J]. Clin Infect Dis, 2009,48(8): 1003-1032.
16
Peterson S, Dugas AF, Rothman RE. Evaluation of 11 commercially available rapid influenza diagnostic tests—United States, 2011-2012 [J]. JAMA, 2013,309(43):873-876.
17
Hazelton B, Nedeljkovic G, Ratnamohan VM, et al. Evaluation of the Sofia Influenza A + B fluorescent immunoassay for the rapid diagnosis of influenza A and B [J]. J Med Virol, 2015,87(1):35-38.
18
Ryu SW, Lee JH, Kim J, et al. Comparison of two new generation influenza rapid diagnostic tests with instrument-based digital readout systems for influenza virus detection [J]. Br J Biomed Sci, 2016,73(3): 115-120.
19
Chen Y, Wang D, Zheng S, et al. Rapid diagnostic tests for identifying avian influenza A(H7N9) virus in clinical samples [J]. Emerg Infect Dis, 2015,21(1):87-90.
20
Sakai-Tagawa Y, Ozawa M, Yamada S, et al. Detection sensitivity of influenza rapid diagnostic tests [J]. Microbiol Immunol, 2014, 58(10):600-606.
21
Zhang WD, Evans DH. Detection and identification of human influenza viruses by the polymerase chain reaction [J]. J Virol Methods, 1991,33(1-2):165-189.
22
van Elden LJ, Nijhuis M, Schipper P, et al. Simultaneous detection of influenza viruses A and B using real-time quantitative PCR [J]. J Clin Microbiol, 2001,39(1):196-200.
23
Nguyen Van JC, Caméléna F, Dahoun M, et al. Prospective evaluation of the Alere i Influenza A&B nucleic acid amplification versus Xpert Flu/RSV [J]. Diagn Microbiol Infect Dis, 2016,85(1):19-22.
24
Nolte FS, Gauld L, Barrett SB. Direct Comparison of Alere™ i and cobas® Liat Influenza A and B Tests for Rapid Detection of Influenza Virus Infection [J]. J Clin Microbiol, 2016,54(11):2763-2766
25
Rappo U, Schuetz AN, Jenkins SG, Impact of Early Detection of Respiratory Viruses by Multiplex PCR Assay on Clinical Outcomes in Adult Patients [J]. J Clin Microbiol, 2016,54(8):2096-2103.
26
Chen JH, Lam HY, Yip CC, et al. Clinical Evaluation of the New High-Throughput Luminex NxTAG Respiratory Pathogen Panel Assay for Multiplex Respiratory Pathogen Detection [J]. J Clin Microbiol, 2016,54(7):1820-1825.
27
Levine M, Sheu TG, Gubareva LV, et al. Detection of hemagglutinin variants of the pandemic influenza A (H1N1) 2009 virus by pyrosequencing [J]. J Clin Microbiol, 2011,49(4):1307-1312.
28
Lee HK, Tang JW, Loh TP, et al. Emergence of G186D mutation in the presence of R292K mutation in an immunocompromised child infected with influenza A/H3N2 virus, treated with oseltamivir [J]. J Clin Microbiol, 2014,52(5):1749-1750.
29
中华人民共和国国家卫生和计划生育委员会. 人感染H7N9禽流感诊疗方案(2014年版). 2014-01-24.
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