将ISO 15189:2022质量体系五大要求融入教学全过程，结合多元教学方法，旨在提升临床实验室管理学教学质量和学生岗位胜任力。

围绕“以学生为中心、以能力为导向、以标准为引领”的改革理念，对标ISO 15189:2022质量体系框架重构了课程内容体系，创新采用了案例教学、问题导向学习、翻转课堂和角色扮演等多元教学方法，并建立了融合过程性与终结性的评价体系。

教学改革有效提升了学生的质量管理理论认知深度、实践应用能力及质量意识，期末考试平均分为82.1±9.4分，较上一年度提升了约6.9%，差异有统计学意义（P＜0.05）；问卷调查从3个维度进行评价，结果显示，超过98%的学生认为课程内容和设计、教学方法和手段、能力提升和学习收获等“有一定帮助”或“非常有帮助”。学生期末评教满意度提高至98.4%。

基于ISO 15189:2022质量体系的多元教学在临床实验室管理学课程的教学改革中得到学生和教师认可，对培养符合行业国际标准的高质量医学检验人才，促进教学与临床实践紧密结合具有重要现实意义。

To integrate the five core requirements of the ISO 15189:2022 quality system throughout the entire teaching process, and adopt multimodal teaching methods, aiming to enhance the teaching quality of the Clinical Laboratory Management course and students' job competency.

Centered on the philosophy of "student-centered, competency-oriented, and standards-led", the reform restructured the course content system according to the ISO 15189:2022 quality framework. It innovatively adopted multimodal teaching methods including case-based learning, problem-based learning, flipped classroom, and role-playing. An integrated assessment system combining formative and summative evaluation was established.

Teaching practice demonstrated that the reform effectively enhanced students' depth of theoretical understanding of quality management, practical application skills, and awareness of quality. The average score of the final exam was 82.1±9.4, representing an increase of approximately 6.9% compared to the previous year, with a statistically significant difference（P<0.05）. Questionnaire surveys indicated that over 98% of students found the course content and design, teaching methods and techniques, competency improvement, and learning gains to be "somewhat helpful" or "very helpful". Student satisfaction with teaching reached 98.4% at the end of the semester.

The multimodal teaching reform in the Clinical Laboratory Management course, based on the ISO 15189:2022 quality system, was recognized by both students and teachers. It holds significant practical importance for cultivating high-quality medical laboratory talents who meet international industry standards and for promoting the close integration of teaching and clinical practice.